Arès is a dark science fiction story that is set in Paris in 2035. The government in France has collapsed. The country is now one of the world's poorest with 10 million unemployed. In order to endure misery and sadness, residents are dedicated to watching extremely brutal fights broadcasted on television and where everything is allowed, even doping! Arès (Ola Rapace) gets by doing some work for the police, but when his sister is arrested and sent to prison he has to do everything he can to save his sister and her two children. He agrees to participate in a broadcasted fight and at the same time be the guinea pig for a new and effective super drug, which can be life-threatening to use.